Biology Topic Practice

The Lock and Key Theory

The lock and key theory is a simplified model used to explain how enzymes show high specificity for their substrates.

Can you describe the active site's role in one sentence?

What is The Lock and Key Theory?

"The lock and key theory is a model explaining the specificity of enzyme-substrate complexes."

Question 1

Which statement accurately describes enzymes at a GCSE level?

Question 2

Why are enzymes described as biological catalysts?

Question 3

Why are enzymes described as biological catalysts?

Question 4

Which statement accurately describes enzymes at a GCSE level?

Enzyme Specificity

The substrate (key) fits into the active site (lock).

The shape of the active site is complementary to the substrate.

Chemical reactions occur while the substrate is bound.

Exam Tip

Remember the keyword "complementary" when describing how the substrate fits.

Want to improve faster?

The fastest way to improve your grade is to practise exam-style questions, identify your gaps, and focus only on what you don't know.

Start practising this topic
Instantly marked • No sign-up

Related GCSE Biology Questions

View all GCSE Biology topics

Verified for 2024/25 Exams

Aligned to current UK Science Specifications

LO

Little & Often Content Team

Science Education Specialists