Production of Monoclonal Antibodies
Monoclonal antibodies are produced from a single clone of cells and are specific to one binding site on an antigen.
What is a "hybridoma" cell?
What is Production of Monoclonal Antibodies?
"Monoclonal antibodies are antibodies that are made by identical immune cells that are all clones of a unique parent cell."
Why are mice used in the production of monoclonal antibodies?
Why are tumour cells mixed with lymphocytes when producing monoclonal antibodies?
Why are the antibodies produced in this method called monoclonal?
The Production Process
Stimulate mouse lymphocytes to make a specific antibody.
Combine lymphocyte with a tumour cell to make a hybridoma.
Hybridoma cells divide rapidly and produce the antibody.
Tumour cells are used because they can divide indefinitely in a lab.
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